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PGT Treatment in India

Dr. Hrishikesh Pai provides comprehensive PGT services, enabling genetic screening for healthier pregnancies.

Pgt Services

What Are PGT Services?

Preimplantation Genetic Testing (PGT) services represent a pivotal advancement in assisted reproductive technology (ART), offering couples valuable insights into the genetic health of embryos before implantation. This innovative approach empowers individuals to make informed decisions about their reproductive journey, ultimately increasing the likelihood of successful pregnancy and healthy offspring.

Understanding PGT Services

PGT encompasses two distinct techniques: PGT-A (aneuploidy screening), formerly known as PGS (preimplantation genetic screening), and PGT-M (monogenic/single gene disorder testing), formerly known as PGD (preimplantation genetic diagnosis). Each technique serves a unique purpose in identifying genetic abnormalities or specific inherited conditions within embryos created through in vitro fertilization (IVF).

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Key Benefits of PGT Services

  • Genetic Screening: PGT-A allows embryologists to screen embryos for aneuploidy, which refers to an abnormal number of chromosomes. By identifying embryos with the correct number of chromosomes, PGT-A reduces the risk of implanting embryos with chromosomal abnormalities, such as Down syndrome or Turner syndrome, leading to higher pregnancy rates and reduced miscarriage rates.
  • Inherited Disease Detection: PGT-M enables the detection of specific genetic mutations or disorders within embryos, such as cystic fibrosis, sickle cell anaemia, or Huntington's disease. Couples who are carriers of genetic disorders can undergo PGT-M to ensure that only unaffected embryos are selected for transfer, minimising the risk of passing on inherited diseases to future generations.
  • Family Balancing: PGT services can also facilitate family balancing, allowing couples to select embryos of a specific gender for non-medical reasons. This option provides individuals with greater control over their family planning decisions and may be particularly meaningful for couples with a preference for a balanced family composition.
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Procedure and Considerations

The process of PGT services typically involves the following steps:

  • Embryo Biopsy: During the early stages of embryo development, a few cells are carefully removed from each embryo for genetic analysis.

  • Genetic Testing: The biopsied cells undergo genetic analysis using advanced techniques such as polymerase chain reaction (PCR) or next-generation sequencing (NGS) to detect chromosomal abnormalities or specific genetic mutations.

     

  • Embryo Selection: Following genetic testing, embryologists identify and select embryos free of genetic abnormalities or inherited diseases for transfer into the woman's uterus during IVF treatment.

It's essential for couples considering PGT services to undergo genetic counselling to understand the implications of the testing and make informed decisions about their reproductive options. Additionally, the availability of PGT services may vary depending on the fertility clinic or ART facility, so individuals should consult with their healthcare providers to determine the suitability and availability of PGT services for their specific needs.

 

PGT services offer couples a transformative opportunity to assess the genetic health of embryos and make informed decisions about their fertility journey. By providing valuable insights into embryo quality and genetic status, PGT services pave the way for safer, more successful IVF treatments and the birth of healthy, genetically screened offspring.