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PICSI Treatment

Dr. Hrishikesh Pai offers PICSI treatment for precise sperm selection, improving fertilization outcomes.

ICSI Treatment

What is PICSI Treatment?

Physiological Intracytoplasmic Sperm Injection (PICSI) treatment is a cutting-edge technique within the realm of assisted reproductive technology (ART) that aims to enhance the success of in vitro fertilization (IVF) procedures. This innovative method involves selecting sperm based on their ability to bind to hyaluronic acid, a substance naturally present in the female reproductive tract, which mimics the natural process of sperm selection that occurs in the female body.

Understanding PICSI Treatment

During conventional IVF procedures, sperm are typically selected for injection based on their appearance under a microscope. However, this method does not take into account the functional quality of the sperm or its ability to interact with the egg in a natural environment. In contrast, PICSI treatment utilises hyaluronic acid, a substance found in the cumulus cells surrounding the egg, to mimic the natural selection process that occurs in the female reproductive tract.

Picsi Treatment

Key Benefits of PICSI Treatment

  • Improved Sperm Selection : By using hyaluronic acid as a medium, PICSI treatment allows embryologists to select sperm that demonstrate high-quality binding ability. This ensures that only sperm with optimal functional characteristics are chosen for injection, potentially enhancing the chances of successful fertilization.
  • Enhanced Fertilization Rates : Studies have shown that embryos generated using sperm selected through PICSI treatment may exhibit higher rates of fertilization and embryo development compared to those generated using conventional sperm selection methods. This suggests that PICSI treatment may lead to improved embryo quality and increased pregnancy rates.
  • Reduced Risk of DNA Damage : Sperm selected through PICSI treatment are less likely to exhibit DNA damage, as the process of binding to hyaluronic acid is associated with sperm that have intact DNA integrity. This reduces the risk of genetic abnormalities in the resulting embryos and may improve the overall health of offspring.
What is Semen Freezing

Procedure and Considerations

The PICSI treatment process typically involves the following steps:
  • Sperm Selection : Sperm samples are exposed to a hyaluronic acid-coated dish, allowing sperm with optimal binding ability to adhere to the surface.
  • Sperm Injection : Embryologists select sperm that have bound to the hyaluronic acid for injection into mature eggs during the IVF procedure.
  • Fertilization and Embryo Development : After sperm injection, the fertilized eggs (embryos) are cultured in the laboratory until they reach the blastocyst stage, at which point they may be transferred into the woman's uterus.

It's important to note that PICSI treatment may not be suitable for all couples undergoing IVF, and additional testing or evaluation may be required to determine its appropriateness. Additionally, the availability of PICSI treatment may vary depending on the fertility clinic or ART facility.

 

PICSI treatment represents a significant advancement in the field of ART, offering a targeted and effective approach to sperm selection during IVF procedures. By harnessing the natural binding properties of hyaluronic acid, PICSI treatment provides couples with a promising option for enhancing the success of their fertility treatment and achieving their dream of parenthood.